How celastrol sensitizes brains to leptin, curbing hunger and obesity

https://www.sciencedaily.com/releases/2019/03/190304134236.htm

Celastrol’s potent anti-obesity effects were widely reported in 2015. Derived from the origins of the thunder god vine, the drug curbed food consumption in obese mice by almost 80 percent, making up to a 45 percent weight loss.

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